Harvard PGP-Lumosity research study for memory and reaction speed

Dear Jeffrey,

The following is an invitation from a third party activity. While this activity is not conducted by Harvard PGP, we thought you might be interested in learning about it. You are receiving this because:

• You are enrolled in the Harvard Personal Genome Project

Note: This activity is reviewed by the Harvard Medical School Institutional Review Board but is separate from the Harvard PGP's study protocol. Third party activities have approval from their own IRB or equivalent when applicable.

Thank you for your ongoing participation!
Harvard PGP

Dear Harvard PGP participant,

We are initiating, in the form of a third party study, a new genomics research project directed at the Harvard Personal Genome Project (PGP) community in partnership with an online gaming platform Lumosity. We invite you to participate in our research study which will measure your memory, attention and reaction speed by playing 6 different Lumosity games. The goal of the research is to identify genetic factors that can help in developing treatments for neurodegenerative diseases like Alzheimer's.

To participate in our study, please log into your PGP profile (https://my.pgp-hms.org) and click on the Third Party Activities link and click on the PGP-Lumosity activity link. You will be directed to a consent page and given your own personal login credentials to perform the games at Lumosity.

We hope that you will participate in our PGP-Lumosity study and have great fun with the set of 6 games that we have specially selected for you!

For more information about the study, visit our webpage at https://wyss.harvard.edu/PGP-lumosity Any questions? Please feel free to contact us at pgpresearch@wyss.harvard.edu

Thank you!

PGP-Lumosity research team