Re: value
I have a great idea. lets speak today if possible
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decide what you would like to call your investment co.
On Mon, Aug 11, 2014 at 7:27 AM, george church <████████████████████> wrote:
OK. Great. I'll contact check with eGenesisBio.com and "Next generation pathology" teams and see who is most ready to take this on. What is the next step after that? --George
From: "jeffrey E." jeevacation@gmail.com
Date: Monday, August 11, 2014 at 9:04 AM
To: george church
Subject: Re: value
lets start on first investment
Below is a first pass list ofpotential investments for the $10M. This may be more information than you wanted at this point (especially given the trade-off between jargon and brevity), but I'm having so much fun, I just wanted to share it. I'm also recording a few extra thoughts, in case they provide "teaching moment" or post-mortem at some point.
| $200,000 | Supercentenarianstudy.com |
|---|---|
| $1,500,000 | eGenesisBio.com |
| $1,000,000 | Sensor-Selectors |
| $1,000,000 | Protein stability & virus resistance |
| $1,000,000 | Pest control |
| $800,000 | Aging reversal |
| $1,550,000 | Next generation pathology |
| $250,000 | Space Genetics |
| $200,000 | Cold-resistant elephants |
| $2,500,000 | 2nd tranche |
| $10,000,000 | Total |
I ) Supercentenarianstudv.com Thirty genomes collected so far on a small budget by James Clement. $200K would get 8% ownership of the company and allow another 30 genomes to be collected, sequenced and therapies patented.
- eGenesisBio.com: Using CRISPR to engineer animals for resistance to infectious diseases and to act as transplantation donors for major organs (initially kidneys) to humans. Co-founded with Prashant Mali and
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Luhan Yang. Already has a couple of contracts and a some rented lab space.
- Sensor-selector technology for optimizing commercial production of (bio)chemicals. Lead by Vatsan Raman.
- 4)New Multi-virus-resistant redox-insensitive organisms. We just protein published cross linking papers based and patents on radically on this. recoded Lead by bacterial Dan Mandell. genomes and/or
Eliminating ecosystem pests and invasive species. Lead by Kevin Esvelt. This will probably be in the news on July 17. Business model similar to the relationship between Amyris and the Gates Foundation for manufacturing anti-malaria drugs.
Making human genetic disease models in organoids and aging reversal using CRISPR and other epigenetic reprogramming factors. Lead by Bobby Dhadwar and Eswar lyer. Possibly mergeable with Sunercentenarianstudy.com
A new sequencing method capable ofdisplacing pan of the medical pathology imaging market and filling in the large gaps in most plant and animal genome sequences. Lead by Rich Terry.
Genome engineering ofhumans for space. Seed money for patent fees, some lab tests and education efforts via pgEd. Lead by Ting Wu.
Making cold-resistant elephants via CRISPR, focusing on blood, subcutaneous fat and wool/hair (based on what is know about cold-resistant animals, Mammoth DNA, and human mutations). Economics could be like the American Bison which recently grew from a hundred to 500,000 as a source oflow cholesterol meat. Lead by Margo Monroe and Justin Quinn. Possibly mergeable with EgenesisBio.
The rest would be set aside as a second tranche for whichever of the above efforts makes best progress first.
--George