HOUSE_OVERSIGHT_028417

i"}, {"range"™:{"length":277,"start":0},"textStyle":" anf-ts-1"}],"layout":"default- body", "role":"body", "text":"Any broad swing in voter opinion could prove difficult for

Mr. Hugin to overcome. Even with Mr. Me nearly 900,000 more registered Democrat House races that have attracted nationa

nendezaé€™s vulnerabilities, s than Republicans, a

New Jersey has and a number of competitive

attention.","type":"text"}, {"bannerType":"any", "identifier":" anf-banner advertisement 3","layout":"ComponentLayout-—

4","role":"banner advertisement", "type":"banner advertisement"}, {"identifier"™:" anf- heading4-1", "layout": "heading4", "role": "heading4", "text":"A once-notorious drug becomes a lucrative cancer weapon", "type":"text"}, {"identifier":" anf-body- 19","inlineTextStyles"™: [{"range":{"length":235,"start":0},"textStyle":" anf-ts-

I"}, {"range™: {"length":235,"start":0},"textStyle":" anf-ts-1"}],"layout":"default— body", "role":"body", "text":"When Mr. Hugin arrived at Celgene in June 1999, the company

was struggling to figure out how to tur which had been approved a year earlier leprosy.", "type": "text "},{"identifier"™: 20", "inlineTextStyles": [{"range": {"leng i"},{"range"™:{"Length":158, "start":0}," body", "role":"body", "text":"Thalomid wa drug that became notorious in the 1960s defects

worldwide.", thalidomid keywords=APP

onc EMOBIL

B&region=written thr

CLO "

profit on its treat a rare s _anf-body-

th"™:158,"start"™:0 textStyle"™:" anf- s Celgenede™s brand name for thalidomide, af

only marketed drug, kin condition caused by

}, "textStyle":" anf-ts-

oug

Thalomid,

ts-1"}], "layout": "default-

an old

ter it was traced to thousands of birth

type™:"text"}, {"additions"™: [{"URL":"https://www.nytimes.com/1997/11/28/us/ banned-is-in-demand.html?partner=applenewséad h&éasset i1d=100000006090758", "range": {"length"”

:61,"start":55},"type™:"Link"}, {"URL":"https://www.nytimes.com/1997/11/28/us/thalidomid

once-banned-is-in keywords=APPLEMOBI

:11,"start":116},"

demand. html ?partner E&region=written thr ype": "Llink"}], "ident

21","inlineTextStyles": [{"range": {"leng 1"},{"range": {"length":358, "start":0}," body", "role" "body", "text: ! 2

new research sugges were smuggling it into the country and clubsaé€ after research sugges Kaposi sarcoma, two serious complicatio

body-22", "inlineTextStyles": [{"range": { i"},{"range":{"Length":187,"s body", "role": "body", "text":"F.D.A. of fi

sold illicitly, took willing to bring thal

the unusual step o idomide to market

=applenewséad

oughé&asset_id=100000006090758", "range": {"length" ifier":" anf-body- th":358,"start":0},"textStyle":" anf-ts- textStyle":" anf-ts-1"}],"layout":"default-

halidomide had fallen into obscurity until the 1990s, ted it could be useful for a variety of diseases. AIDS activists

selling it through black-market A4€ebuyers

ns of AIDS." "length":187,"start":0}, "texts

tyle™:

cials, =f seeking out drug companies t

when

ted the drug could be used for AIDS wasting syndrome and ,"type™:"text"}, {"identifier"™:

_anf-

ani-ts= tart":0},"textsStyle":" anf-ts-1"}],"layout":"default- alarmed that a notorious drug was being hat might be

legally.","type":"text"}, {"bannerType":"any","identifier":" anf-banner advertisement 4","layout":"ComponentLayout-—

4","role":"banner advertisement", "type":"banner advertisement"}, {"identifier"™:" anf- body-23","inlineTextStyles": [{"range"™:{"length":109,"start":0},"textStyle":" anf-ts- i"}, {"range"™:{"length":109,"start":0},"textStyle":" anf-ts-1"}],"layout":"default-

body", "role": "body", "text":"Celgene, never sold a drug, ultimately took up t challenge.", "type": "text"}, {"additions" disease/clinical-

center. html", "range": {"length":38, "star 24","inlineTextStyles": [{"range": {"leng im}, {"range"™:{"Length":251, "start":0}," body", "role":"body", "text":"In 1998, erythema nodosum leprosum, a complicati United States. In 2007, Celgene said th treat the skin condition.", "type": "text 25", "inlineTextStyles": [{"range": {"leng 1"},{"range"™: {"Llength":256, "start":0}," body", "role":"body", "text":"But leprosy was to keep the drug from harming infan up a first-of-its-kind distribution sys preapproved doctors and pharmacies.","t 26", "inlineTextStyles": [{"range": {"leng i"},{"range"™:{"Length":320,"start":0}," body", "role":"body", "text":"Celgene, me generating intens xcitement in the me clear it would not stop at treating lep

he :({"URL":"https://www.hrsa.gov/hansens-

on of leprosy, which is extremely rare in at just 100 prescriptions a year were wri "},{"identifier":" anf-body- th":256,"start":0},"textStyle":" anf-ts- texts was LS, tem that would limit prescriptions to ype": "text"}, {"identifier":" anf-body- th":320,"start":0},"textsStyle":" anf-ts- texts anwhile, had ambitious plans. dical world, rosy.

hardly the point:

Thalidomide

tyle":" anf-ts-1"}],"layout"™:"default The F.D.A.a4€™s main goal and it did so by requiring that Celgene set

then a little-known New Jersey company that had

C":113},"type"™:"Llink"}],"identifier":" anf-body- th™:251,"start":0},"textStyle":" anf-ts- textStyle"™:" anf-ts-1"}],"layout":"default-

Celgeneae™s application was approved to treat

the tten to

tyle":" anf-ts-1"}], "layout": "default-

was

and from the start the company made Celgene needed a finance executive to

HOUSE_OVERSIGHT_028417