To: Jeffrey Epsteinfleeyacation©gmail.com] From: Ted Kaptchuk Sent: Mon 7/16/2012 6:18:46 PM Subject: Hi Jeffrey Hope you're enjoying some of the long days of summer. I just wanted to update you on the progress of our center in placebo studies. Besides moving forward in some exciting studies and new publications, we have just received a $250,000 grant from the Pioneer Fund of the Robert Wood Johnson Foundation to pursue initiatives to integrate placebo studies into the education framework of Harvard University. Also, the Food and Drug Administration (FDA) has asked to collaborate with us to develop new research designs that would more efficiently control for placebo effects in randomized trials. We're hoping that this will attract collaboration from the pharmaceutical industry. I also wanted to mention that we're are continuing to search for partners in the private philanthropic community. Best wishes, Ted Ted J. Kaptchuk Associate Professor of Medicine Harvard Medical School Director, Program in Placebo Studies & Therapeutic Encounter Beth Israel Deaconess Medical Center Boston, MA 02215 Phone: Email: Web: www.programinplacebostudies.org EFTA_R1_00290646 EFTA01879209