To: From: Jeffrey Epstein Sent: Wed 7/18/2012 4:32:28 PM Subject: Re: coma its a great wiring diagram„ doesn't seem like only a two way two lane highway, no matter how many makes and models traverse, it . what do we know about lesions in the area.. , why do they connect the vns so high , close to the brain, why does it only inhibit heart rate. On Wed, Jul 18, 2012 at 12:21 PM, wrote: the issue with coma is that there are structural, metabolic, vascular and other reasons for coma that all act different. people have tried to argue a "final common pathway" idea when they study consciousness but not sure that holds water. maybe human studies of coma patients with VNS would be super cool but would never pass IRB (human subjects). I would do it in a second. For four years I tried to convince the IRB to let me put a coma patient's hand in ice water while doing a SPECT scan (that we were already doing for diagnostic reasons) and it never got approved Coma patients are super hard BTW I have the largest data base of coma patients since I have kept every image and record of all patients i've seen. Two years ago I saw my 1,000th coma patient. Give lots of lectures on coma. —Original Message-- Front Jeffrey Epstein'c > To: Sent: Wed, Jul 18, 2012 7:09 am Subject: Re: Dinner w Boris right now i don't think so. , i would like to know how it behaves when disconnected.. if it is only telemetry , all things should go dead,. if it is fact calcuating and inhibitoing locally„ no need for telementry alone. I think it is brain , I am surprised that we only have one brain„ it makes little sense where everything should be redunadant , degenerative. it would explain coma behavior. . main brain down, etc. i would like to see vns aplied to coma patients. On Wed, Jul 18, 2012 at 10:02 AM, ‹ > wrote: 2 way telemtry From: Jeffrey epstein Sent: 7 18 2012 4:23 AM To: Subject: Re: Dinner w Boris right now EFTA_R1_00281253 EFTA01873692 I am intrigues , it looks more like brain than nerve Sent from my iPad On Jul 18, 2012, at 12:08 AM, We miss you Well, I do anyway ************ • ' • ********Ittitir*****1****** The information contained in this communication is confidential, may be attorney-client privileged, may constitute inside information, and is intended only for the use of the addressee. It is the property of Jeffrey Epstein Unauthorized use, disclosure or copying of this communication or any part thereof is strictly prohibited and may be unlawful. If you have received this communication in error, please notify us immediately by return e-mail or by e-mail to jeevacation@gmail.com and destroy this communication and all copies thereof, including all attachments. copyright -all rights reserved wrote: ************************************ * * * * * * * * * * * * * * * * * The information contained in this communication is confidential, may be attorney-client privileged, may constitute inside information, and is intended only for the use of the addressee. It is the property of Jeffrey Epstein Unauthorized use, disclosure or copying of this communication or any part thereof is strictly prohibited and may be unlawful. If you have received this communication in error, please notify us immediately by return e-mail or by e-mail to jeevacation@gmail.com, and destroy this communication and all copies thereof, including all attachments. copyright -all rights reserved EFTA_R1_00281254 EFTA01873693